Best NRFI Bets Today: Top No Run First Inning Picks & Predictions for July 22

My best NRFI bets today break down the top no run first inning picks across Wednesday's MLB slate with pitcher matchup analysis for each game.
San Diego Padres starting pitcher Michael King - who's featured in my best NRFI bets today - throws a pitch in the first inning.
Pictured: San Diego Padres starting pitcher Michael King - who's featured in my best NRFI bets today - throws a pitch in the first inning. Photo by: Peter Aiken-Imagn Images
Enjoying SBR content? Add us as a preferred source on your Google account Add as a preferred source on Google

🤑 Best NRFI Bets Today for Wednesday (July 22)

We're 10-3 on our NRFI bets over the last couple of weeks, and we're looking to stay hot on this fine Wednesday after going 0-1 yesterday. Today, we're backing high strikeout rates for Rays vs. Blue Jays and Padres vs. Braves to get the juices flowing. Let's bring those units home with our best NRFI bets today.


โšพ Best NRFI bets today: Wednesday, July 22

See all of our expertsโ€™ MLB picks based on the latest MLB odds. Odds via FanDuel.

โšพ NRFI pick ๐Ÿ’ต Units ๐Ÿ“ Notes
Rays vs. Blue Jays NRFI (-128) 2u โ†’ 1.56u Fisher owns 29% K rate vs. Rays
Padres vs. Braves NRFI (-115) u -> 0.86u Braves own just .290 xwOBA vs. King

Total wagered: 3 units | Max profit: 2.42 units

📃 Affiliate disclosure

Sportsbook Review may receive a commission if you sign up through our links. Not intended for use in MA. Bonuses not applicable in Ontario. 21+ only. (Gambling problem? Call 1-800-GAMBLER)


๐Ÿ’ฐ Best NRFI bets today (Wednesday, July 22)

Rays vs. Blue Jays NRFI (-128) - 7:07 p.m. ET

  • Griffin Jax (4.08 ERA) vs. Braydon Fisher (3.65 ERA)
  • NRFI records: Rays (52-48) vs. Blue Jays (48-53)

The Blue Jays' offense is just a tirefire right now, having scored just four runs across their last four games. That's ... not good. It doesn't get any easier tonight with Jax on the mound for the Rays - he's limited Toronto to a .203 AVG (.262 xBA) across 74 plate appearances. We'll see three outs today. On the other side is the serviceable Fisher, who's had Tampa's number in his short career. The big righty is striking this team out at a 29% clip and limiting them to a .176 xBA, which includes holding Jonathan Aranda (0-for-3) and Junior Caminero (1-for-5) in check. I'd price this play closer to -150 - we love that type of value.


Padres vs. Braves NRFI (-115) - 7:15 p.m. ET

  • Michael King (3.34 ERA) vs. Martin Perez (3.54 ERA)
  • NRFI records: Padres (61-40) vs. Braves (46-54)

We've got a fairly large sample size to draw from here, with a combined 187 plate appearances against these two pitchers. Across 81 at-bats against him, King is limiting this Braves team to a .248 xBA and .290 xwOBA. Atlanta's top three hitters in Drake Baldwin, Ozzie Albies, and Matt Olson are a combined 3-for-20 against the righty - that'll play. For Atlanta, Perez has limited Fernando Tatis Jr. to a .191 xBA over five at-bats, which should help us start the game with an out. Let's fire this play up with confidence as part of our best NRFI bets today.

💣️ More MLB player props for Wednesday

Looking for more plays? Look no further than Sean Tomlinson's best home run predictions today or my best strikeout props today.


๐ŸŽŸ๏ธ Most-bet NRFIs today

Betting insights via BetMGM.

1. Pirates vs. Yankees Game 1 (-105)
2. Mets vs. Brewers (-140)
3. Giants vs. Royals (-120)
4. Orioles vs. Red Sox Game 1 (+100)
5. Twins vs. Guardians (-120)


๐Ÿ’ต My betting record for MLB picks

All MLB picks, including SGPs, have been tracked since March 26.

Bet type Record Net profit
NRFI picks 55-48 +6.66 units 

๐Ÿ’ก How I'm betting NRFI picks today (July 22)

Follow all of our MLB analysis and expert predictions for baseball season.

A NRFI (No Run First Inning) bet carries high variance, meaning success requires a disciplined, daily dive into the data. Before placing a wager, run through a strict checklist: analyze how the starting pitcher matches up against the top three hitters in the lineup, track underlying metrics like strikeout rates (K%) and expected batting averages (xBA), and review recent team-specific first-inning scoring trends. Because a single mistake or lucky hit can ruin the bet instantly, always use this daily routine to guide your wagers and scale your unit sizing accordingly to protect your bankroll.