Best Strikeout Props Today: MLB Expert Picks & Player Props for Wednesday, July 22
Last Updated: July 22, 2026 12:25 PM EDT • 2 minute read X Social Google News Link
Welcome back to our best strikeout props today for Wednesday, July 22, after sweeping the slate twice last week.
Who's generating some whiffs (or lack thereof) for us on Wednesday? We're locking in Max Fried and Seth Lugo to get the job done and win us a couple of bets. Let's dive into my best strikeout picks and predictions using odds from the top sports betting sites.
⚾ Best strikeout props today: Wednesday, July 22
See all of our experts’ MLB picks based on the latest MLB odds. Odds via FanDuel.
| ⚾ Strikeout pick | 💵 Units | 📝 Notes |
|---|---|---|
| Max Fried Under 3.5 strikeouts (+114) | 2u → 2.28u | Fried owns 17% K rate vs. Pirates |
| Seth Lugo Under 4.5 strikeouts (-120) | 1u -> .83u | Lugo owns 10% K rate vs. Giants |
Total wagered: 3 units | Max profit: 3.11 units
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💪 Best MLB strikeout predictions today
Here's a breakdown of my best MLB strikeout prop predictions and expert picks today. Check out the rest of our MLB picks along with our guide on how to bet on MLB.
Max Fried Under 3.5 strikeouts vs. Pirates (+114)
We have a large sample size to work from here, with 50 at-bats from the Pirates against Fried to draw from. With the lefty owning just a 17% K rate and 24% whiff rate against this lineup, we're feeling pretty good about this plus-money Under. Not only are his numbers lacking in this specific matchup, but Fried will be returning from injury today, which makes me believe he'll have issues going deep against the gritty Pirates. Let's fire this play up as part of our best strikeout props today.
Seth Lugo Under 4.5 strikeouts vs. Giants (-120)
Lugo quite simply just doesn't miss bats, and it's a problem for him and the Royals this year. The righty has just a 10% K rate against the Giants and is in the sixth percentile for whiff and chase percentage this year. He's having one of the worst seasons of his lengthy career in terms of strikeout rate and xERA, too. His steady decline makes him a perfect choice to go Under against a team that strikes out the fifth-least in MLB.
🤑 More MLB player props today
Looking for more plays? Dive into Sean Tomlinson's best home run predictions today today or my best NRFI bets today.
🎟️ Most-bet MLB player props today
Betting insights via BetMGM.
| Player | Team | Bet | Odds |
|---|---|---|---|
| Henry Bolte | A's | Under 1.5 hits, runs & RBIs | +100 |
| James Wood | Nationals | To hit 1+ home runs | +240 |
| Brandon Nimmo | Rangers | To hit 1+ home runs | +650 |
| Sandy Alcantara | Marlins | Under 18.5 outs | -125 |
| Aaron Nola | Phillies | Under 15.5 outs | -140 |
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